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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1431a012b68fa911364a2731df7a827c7a1d2ee7976597a7018909142cdcd6' 
  AND token = 'XITrNuntGFtSLH8pn2ChC59nqddAWvQNH9o2hr5KLIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}