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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3badd177d6e3238b6baaaff04812c9f3dd0e6443649e980333a518b4c40b057' 
  AND token = 'G7HhRoopY5uXqmz21TufkPvBdJhtmZD2PrbDy5iWJJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}