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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6535d242d895c25cb0cd0e86accba52c8ff6d3dd80e39b672af9d1b27d94aabe' 
  AND token = 'B66yz9QNVe9XACP5wQP5ZXnn81PcCYwdobT29A50hEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}