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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b52a870e528e70f4fded11b2149715b12a821f8dfce500c4eb2a3aad428615b' 
  AND token = 'RHjvB5+5nh3zWKEAhGeZrwrrYHjSH1nX4P4ne+qM02c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}