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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1985a5ad70c49e7d51c1620b4066ac8992ed75b80792f9486d90cacdc5fc2e7' 
  AND token = 'ynV2DDk8y+SO5hA4KkzGWliXDt+zb2j7nQ9qReB7GQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}