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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6035f4a88af2917d7a585a7ae4e69df4820611eb34925a200ace1f1b5941718f' 
  AND token = 'FdQrc+ZGZ1+p+3b6yWQApCos7A/h6DSzuLApzyxeqFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}