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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '179d9dd77a46a2ab6381f7edc5fd2969d8e414cc9d60675ad39ee01ea42bd27f' 
  AND token = 'WXQZcFIp3/2q1c3WjmfvYzYoKuUCuujV30Nov8CeEVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}