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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837574e4ef57b81fc5d6ef9903b6c3e10c46dc353f4c30ffbc232c7d82322486' 
  AND token = '0Tc7f6VuQN9c/z3Lih+jQMQXRt7qxHCEQfbpCh9+PBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}