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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741ab533e434a6a5aef50bba1906ac769f514f547f893d6ff4c22ccde6f3e8c5' 
  AND token = 'Ca7FkoHR8vAEZy6zF8UQ4Otqn4/M+vSI1bOpzVZsKdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}