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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12cced732d405475c3784ff4bc2234487bd795de7d2b778b4a428904abba97d' 
  AND token = '7u0fQa+JD9vD5HQN1XgUz3zx2PSDxCGeWStDy4LvvVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}