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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e0f8c617145617efe37e0f45c0734ac17de973c56e60d3961dbf1d434d314c' 
  AND token = 'EhfVEfu51g4mNwPWq2p9EASvIK0Xbj6vX8/jwHLTRo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}