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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5080e468ffcfc6269b371660dc7b21a330dc0e0467d8a9d63e15aaf35b4bfcf' 
  AND token = 'OFVB8a3puK5ivJST6N3eTx0uQj6WNaub//AZvlQ3nJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}