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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c8fe0eb24220a2414873277cbb877d75594c671ee5a3d9bd23831545826943' 
  AND token = 'NK2Rm39kpnDv1CMsCF5djcZjZ6GUmW5nDBzlt5qrSMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}