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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b16da43c8ad6add7cf0d05febc0e823521e39977e7eb73469a2096c8af5fe3' 
  AND token = 'Q3/7XAEt5T1Swgqm0PcyYUHnG8uMvb2KM9y8kfDLYp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}