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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2fc69461c20e2e96948c26eff97bb0cd13b604fa5fc21108f4e825e63f6d755' 
  AND token = 'icdIUUdxh4s0XJ0h86XdgVezpq6T1slPbVyIzCFlkPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}