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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd9486ce5aa902776d03789373161e042a47912ddbf6096c5efb8e1e56d0ca4' 
  AND token = 'TcmbnlqQsNtYh+oJSdeKB0N28IZrDNwgdUGNpl1wWtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}