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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc2d461dea4e9ff83a14a5b119c2ff891fb40fba0ce34bdfa2a941f6b406625' 
  AND token = 'JQNwkGI72ZxLY2+s8cfgpNhoVIZ8YEONAbyDei4xN0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}