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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15edfd70e9a266bae7f03eb430b1c6d5e515374b2863161d7207abc1301778b3' 
  AND token = 'cuttlM3gTN4JxvTVCHR+7hUlEEOG/ZvNtzEOZ4pneIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}