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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6662ab97d89d298f418105ff75469909e4c3350b5a095f7541a0d42f8f92df50' 
  AND token = 'ldWSZTo8XgUbAxl+zRf3ULzNZrcTCacJHv5DJh+tvaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}