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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6209ac0176d576bf67e2b78ad03a0e7c67b784d80ddf1e79d4cde2fefdd256d1' 
  AND token = 'Sx/K7JgIeRq7WHkiMD0zqvur51jtk215EMnx+TwjeaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}