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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7b4a890af8a33923ae12b87a85ded8b2d30bc01b2bde16db7cc044120b5468' 
  AND token = 'izheyU4Ic11PI3yN/xqijqwEwsAycTY3wssRY+e5ETg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}