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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d9a3c00595460b912dfd5fea22d218a3f35614e462b47f37b69ac07652a0881' 
  AND token = 'mYnaVPdOIr8bm0o+Vi01mNkK/lFQqTorjmSItTjgvNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}