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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee936398247f9562846abae542f14ee21974b3dccbcff1ac7e0f2c112266f69' 
  AND token = 'l5e91360DAsEWOjXMibU2Nkk4y4AiDUKcTDSXgXWej4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}