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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8e282064ab3cf40d9d88eb14c08a153bdd02d80c32584c2c6eec004ad3c10d' 
  AND token = 'XTekU6YJFX04qYk3MylfGt1O/6VHA7Hfs4AGVUIZ8qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}