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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d1c21cadfee0f71ddb20c26d40c81a7b5fa326adb0db1cff914d1b0009c327' 
  AND token = '9h8bWo32gLLg9QOapv615RS8wfgQfu5cF0+sxyX/+lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}