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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16d1e6698863f5c7380b6d8eea533e20a7bc7e3cbcbe1a481f19bfbed787197' 
  AND token = 'plxaE8brOURK8WnHiY2PN36fFsiOI1rItSDBPfr71RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}