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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0863724b8a04d272859d164ba11ed224f0f1de152adb1955f727529d220b170' 
  AND token = 'dGB/5uGQjhCnC8rtgswsBs1kYVpBwqcB2uYV/rF4waY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}