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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6645eb660a6adf63af7bd72e08c66330ab2726eb30e5bce155c0202348f3be03' 
  AND token = 'K3pABxMWbVZIp/HFhUBOIpEzf5DrFX8FFNnInowCOR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}