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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1345c08f00d0ee541fa62581549afa4ca01c1c5beb1ec82adcc7654b75b046d' 
  AND token = '8WZ/YAFRZKAVXfuqvVUgi7JIGU/p8Avhb6gzNzSnct4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}