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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f5a8b5e06c114cf79d5c3370d30415ced37dbe4c5129f944574b14233aabe4' 
  AND token = 'fdNmPVH57xowJ+YUcSxVSUOsKUT1cCvQgQFya8K61B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}