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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2916cddbc34f58f573ed9c82379f44028148fbd15d72033d3d49252e2d8245' 
  AND token = 'Y7PaBQz+u5N8FcHgvZH7ytA7Dw1NchsF8dM0mX/y3Ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}