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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb5a848d385ea5e2a004436adc609fb76440a6cc89ac9b26260b442e0a0ecc38' 
  AND token = 'oyMBUs+ZgxcIMOexighdRtdCgZErJU3Fu3XKCS3iWT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}