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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f58671ef4945131c21be18a28be80bf080da12521b67e37589b02121f926b59' 
  AND token = 'VYJbC5nZnsARcIbqZ0XLUM2lFm+mgklcbYOG46lmht0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}