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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18f83217e4fb0641eb55a04340c3fad6fbd5bae65762d0f600866c16b55d55c' 
  AND token = '0PWr435ZunCUpb6H9dELk6FGGsDz5J2khnxmZmZbb2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}