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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0d7aa1af71c04c125e1922505a39edfb0e4586dea8d66e6f7d121a9d43b922' 
  AND token = 'vhOmoDW33CpYnHM8J7KIFRwSnk12YCNrmSHQ6p8xfcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}