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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2cf174bdaa2aadb5a16f45112a375180e9499e0a367f27eef72c0bb826b7fd4' 
  AND token = '0Gxd4kkeGVHSQr5HwkFT2yU/Ctb01opLo6hWTRWMMtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}