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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f9bccdc3eb85482570c7e51180f561a78faffa4699c1d81ddb02c036b8cc09' 
  AND token = 'jeWXL51QY52Md+tlsVT4xMdgTqrMVAsfbMVfU9WIHEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}