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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54b30a21ca02b22d7c7ea3627e542db8a125cac66c0b0b7b16f40ef4d7de404' 
  AND token = 'oDhX1cDrBLG2ojym+Ez2OTcQnOlij3k7fFP8wNdeNoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}