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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a735ee0f0e517bdb9f603b78f831efe2ab1ebb0d51e28cea2f903308422075' 
  AND token = '8rmYbNBKA/g1QEEXxW6tn+0581Hqmksa7qrslU9X1FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}