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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208f8a9966677c740781ab6ad9ab2cd9f43f0d67287b1de6d436a4f29066bc06' 
  AND token = 'siCdMpIG7CthsZoi0HuFYtQLXq4b/FDNptNg8jhlf4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}