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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308c279b49ed96f866c424a494ea0c908cf5cc67453e080d72125766813c6a15' 
  AND token = 'o2/YxLIvYn2yN7qqqsW9yLyQweGYmXSGN0aQBkhqmJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}