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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f729caf47df72f92f36c8e2a3cf621ee13b954090b1bb212ff556e3c5a371130' 
  AND token = 'q3EzPJQgManOHujfik6o1liNkjjQu8U1c49XYhrx2KU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}