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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6ce76b0700c01385b1e76de87d56b0cca03a6c13ea6c636c9b45193bb8e2e9' 
  AND token = 'vY5SAv5/Segft6qXJf+y3VdPRUmaYMWbQmxRNlLSjl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}