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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f42e6f8ac0c7345707e65c0e1dc91aa8731d558e1b157121cb75c31fe7c60568' 
  AND token = 'NeSQ6NVryoH110c+B5kfzxrnYVNvov85WdVtD9/Lma0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}