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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e9e4a7e43f5ea271b260f893eee86d16d9f5d3dde80ed5d22fd39e2a9777e6' 
  AND token = 'A+M0NK+sRD9S5fGQlEGCF3JkWhQEwwlMMM4AGhTsqe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}