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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bd38086ae65c7f264f078a023dbdf942be0f013fa03e0d879619218f54d4fd' 
  AND token = 'm2Vf/i0SB8veX6G+tkSMYMNYYsQFWjiaBDVNuDD/cxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}