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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e46e2ef39deae18f7a22eca571aad6843bb94c1ab69695ab1e4828662555d77' 
  AND token = '8hpGwkP8inFRi9G0HbZVorbS680jEQ+dm0TLz378AcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}