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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b32d727b91f95edb889117dcdd64cd6a825a5269b29cc1ae2c458c9e4bf772f' 
  AND token = 'pXUN1QwwEv/a+dDHgjE/oJQ1eioyPaxRes6xxYiLrko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}