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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ce50557549d78c88eb0bc14728e2b3d709cccdb6881c981ae26d9df3bf3a0f' 
  AND token = 'ocFivPfnw3e5P5W5SdzqBQz9CmmzGN5bdV498+OpF60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}