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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1e784464ddeb04ced0d3ea37d5d962f74571ee0c2cec5c0b39bd972c7b1161' 
  AND token = 'MEH3lo4eyDhIOEneeRar6ev1t4fEY7lHTb71h5PINno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}